How to deal with 18yr old son who doesnt listen to parents ?

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My son is a high school senior and last year he was just ur normal teenager but since his senior year has started he has not been going to school, we have caught him smoking, we have taken his cellphone but whatever we say to him he just says he doesnt care and we truly dont know what to do does any1 have any tips on how to deal with this, thanx for any help in advance
to answer mark grvr yes we have already caught him sellin drugs and he has stop since but the behavior still has not changed and as for moving him out i dont think my wife would be okay with that

let him move out and face the real world.